Epithelial cells in the gut continue to be active in mice even after the stimulus or infection disappears, which may be a source of chronic intestinal pain associated with irritable bowel syndrome
May 6, 2022
Chronic bowel pain in people with irritable bowel syndrome (IBS) may be associated with prolonged activation of rare intestinal cells. In mice, these cells continue to respond to stimuli even after the substances have left the gut.
IBS affects up to 15 percent of the U.S. population and is two to six times more common in women than men. The disease is characterized by symptoms such as bloating, abdominal pain and hypersensitivity to certain foods and irritants, despite …
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